About this item
SCF is a multipotent factor which affects cells of the myeloid, erythroid, mast, and lymphoid lineages. Exists both as a membrane-bound and soluble form. Expressed by fibroblasts and endothelial cells promoting proliferation, migration, survival, and differentiation in hematopoietic progenitors, melanocytes, and germ cells.
- High quality
- Low endotoxin
- Lot-to-lot consistency
- Animal free Manufactured following GMP guidelines
Promotes mast cell secretory function, chemotaxis, and adhesion. Enhances secretion of mediators in response to IgE-dependent activation. The biological activity of CTGrade GMP interleukins and growth factors is standardized, where applicable, to WHO International standards, providing cell and gene therapy developers consistent, lot-to-lot biological activity and performance.
Host cell protein: ≤30 ng/ml; Host cell DNA: ≤0.01 ng/ml; Sterility testing: No growth; Mycoplasma: Negative
Specifications
- Conjugation:Unconjugated
- Protein Function:Cytokine
- Protein/peptide type:Recombinant
- Source:E. coli
- Species:Human
- Storage conditions:At or below –20 °C
- Endotoxin content:Endotoxin LAL (EU/µg) ≤0.05
- Biological activity:Bioactivity assay: Proliferation of TF-1 ; ED50 ≤15 ng/ml; Bioactivity ≥1.0x10³ IU/µg
- Gene ID:P21583
- Reconstitution instructions:Sterile water at 0.1-0.5 mg/ml
- Endotoxin-free:N
- Carrier-free:Y
- Protease-free:N
- Animal-free:Y
- Protein synonyms:c-Kit Ligand|KL|Steel Factor|MGF
- Protein/peptide name:SCF
- Purity:≥97%
- Molecular weight:18.6 kDa
- Sequence:MEGICRNRVT NNVKDVTKLV ANLPKDYMIT LKYVPGMDVL PSHCWISEMV VQLSDSLTDL LDKFSNISEG LSNYSIIDKL VNIVDDLVEC VKENSSKDLK KSFKSPEPRL FTPEEFFRIF NRSIDAFKDF VVASETSDCV VSSTLSPEKD SRVSVTKPFM LPPVA
- Endotoxin level:Low
- Formulation:10 mM sodium phosphate, 50 mM sodium chloride, pH 7.5
- Nuclease-free:N
- Grade:GMP
- Shipping temperature:Ambient
- Tested applications:Bioassay