Human Recombinant SCF (from E. coli)

Supplier: VWR International

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Supplier: VWR International

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About this item

SCF is a multipotent factor which affects cells of the myeloid, erythroid, mast, and lymphoid lineages. Exists both as a membrane-bound and soluble form. Expressed by fibroblasts and endothelial cells promoting proliferation, migration, survival, and differentiation in hematopoietic progenitors, melanocytes, and germ cells.

High quality
Low endotoxin
Lot-to-lot consistency
Animal free Manufactured following GMP guidelines

Promotes mast cell secretory function, chemotaxis, and adhesion. Enhances secretion of mediators in response to IgE-dependent activation. The biological activity of CTGrade GMP interleukins and growth factors is standardized, where applicable, to WHO International standards, providing cell and gene therapy developers consistent, lot-to-lot biological activity and performance.

Host cell protein: ≤30 ng/ml; Host cell DNA: ≤0.01 ng/ml; Sterility testing: No growth; Mycoplasma: Negative

Caution: For research use or further manufacturing only.

Specifications

Conjugation:
Unconjugated
Protein Function:
Cytokine
Protein/peptide type:
Recombinant
Source:
E. coli
Species:
Human
Storage conditions:
At or below –20 °C
Endotoxin content:
Endotoxin LAL (EU/µg) ≤0.05
Biological activity:
Bioactivity assay: Proliferation of TF-1 ; ED50 ≤15 ng/ml; Bioactivity ≥1.0x10³ IU/µg
Gene ID:
P21583
Reconstitution instructions:
Sterile water at 0.1-0.5 mg/ml
Endotoxin-free:
N
Carrier-free:
Y
Protease-free:
N
Animal-free:
Y
Protein synonyms:
c-Kit Ligand|KL|Steel Factor|MGF
Protein/peptide name:
SCF
Purity:
≥97%
Molecular weight:
18.6 kDa
Sequence:
MEGICRNRVT NNVKDVTKLV ANLPKDYMIT LKYVPGMDVL PSHCWISEMV VQLSDSLTDL LDKFSNISEG LSNYSIIDKL VNIVDDLVEC VKENSSKDLK KSFKSPEPRL FTPEEFFRIF NRSIDAFKDF VVASETSDCV VSSTLSPEKD SRVSVTKPFM LPPVA
Endotoxin level:
Low
Formulation:
10 mM sodium phosphate, 50 mM sodium chloride, pH 7.5
Nuclease-free:
N
Grade:
GMP
Shipping temperature:
Ambient
Tested applications:
Bioassay