Rat Recombinant IL-17A (from E. coli)

Supplier: VWR International

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Supplier: VWR International

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About this item

Interleukin 17A (IL-17A), also known as CTLA-8, is a member of the IL-17 family of proteins. IL-17A is a proinflammatory cytokine that is secreted by activated CD4+ and CD8+ T lymphocytes. IL-17A acts through its receptor, IL-17R, to promote increased cytokine and chemokine secretion. In turn, the cytokines and chemokines mediate the immunoregulatory function of IL-17A by promoting the proliferation, maturation, and chemoattraction of neutrophils to inflammatory sites. Elevated levels of IL-17A are associated with rheumatoid arthritis, airway inflammation, allograft rejection, inflammatory bowel disease, psoriasis, cancer, and multiple sclerosis. Human, mouse, and rat IL-17A show activity on mouse cells.

High quality

Low endotoxin

Affordable

Caution: For research use only.

Specifications

Conjugation:
Unconjugated
Protein Function:
Cytokine
Protein/peptide type:
Recombinant
Source:
E. coli
Species:
Rat
Storage conditions:
–20 °C
Endotoxin content:
Endotoxin LAL (EU/µg) ≤1
Biological activity:
Bioactivity: No biological activity data is available at this time
Gene ID:
Q61453
Reconstitution instructions:
Sterile water at 0.1 mg/ml
Endotoxin-free:
N
Carrier-free:
Y
Protease-free:
N
Animal-free:
N
Protein synonyms:
IL-17|CTLA-8
Protein/peptide name:
IL-17A
Purity:
≥95%
Molecular weight:
15.1/30.3 kDa
Sequence:
MAVLIPQSSV CPNAEANNFL QNVKVNLKVL NSLSSKASSR RPSDYLNRST SPWTLSRNED PDRYPSVIWE AQCRHQRCVN AEGKLDHHMN SVLIQQEILV LKREPEKCPF TFRVEKMLVG VGCTCVSSIV RHAS
Endotoxin level:
Low
Formulation:
10 mM sodium citrate, pH 3.0
Nuclease-free:
N
Grade:
RUO
Shipping temperature:
RT