Human Recombinant BD-3 (from E. coli)
Supplier: VWR International
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About this item
Beta-Defensin 3 (BD-3), also known as DEFB-3, is a member of the defensin class of antimicrobial peptides. Beta defensins exert host defense responses against viruses, bacteria, and fungi through the binding and permeabilizing of microbial membranes. BD-3 expression is stimulated by interferon-gamma and is an important molecule during adaptive immunity.
- High quality
- Low endotoxin
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BD-3 functions to activate monocytes and mast cells, and has antibacterial functions towards Gram-negative and Gram-positive bacteria. Further, BD-3 blocks human immunodeficiency virus type 1 (HIV-1) replication through the downregulation of the HIV-1 co-receptor, CXCR4.
Caution: For research use only.
Specifications
- Conjugation:Unconjugated
- Protein Function:Cytokine
- Protein/peptide type:Recombinant
- Source:E. coli
- Species:Human
- Storage conditions:–20 °C
- Endotoxin content:Endotoxin LAL (EU/µg) ≤0.1
- Biological activity:Bioactivity: No biological activity data is available at this time
- Gene ID:P81534
- Reconstitution instructions:Sterile 10 mM acetic acid at 0.1 mg/ml
- Endotoxin-free:N
- Carrier-free:Y
- Protease-free:N
- Animal-free:N
- Protein synonyms:DEFB-3
- Protein/peptide name:BD-3
- Purity:≥95%
- Molecular weight:5.2 kDa
- Sequence:GIINTLQKYY CRVRGGRCAV LSCLPKEEQI GKCSTRGRKC CRRKK
- Endotoxin level:Low
- Formulation:0.1% trifluoroacetic acid (TFA)
- Nuclease-free:N
- Grade:RUO
- Shipping temperature:RT
Specifications
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