Assay-specific Crystal Flex Probes and primers for the detection of BRAF mutations and its Positive Control. BRAF (drop-off V600-K601) Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify mutations codons V600 and K601 of the BRAF gene. BRAF is pivotal in regulating cell signaling pathways implicated in cancer development, notably melanoma, colorectal cancer and thyroid cancer, through its role in the MAPK/ERK pathway.

• Ready-to-use assay reagents to detect multiple targets in a single reaction
• Crystal Flex Probe detection chemistry for flexible assay configuration
• Same set of crystal universal reporters to detect any target in different assays

Wet lab tested
Compatibility: Nio™ Digital PCR, Prism6, Prism3, ruby chip
Channels: Green, blue
Required reagents: Crystal universal reporter 3 and naica® PCR MIX 10X
Target: BRAF V600-K601