Anti-CD69 (AIM) Mouse Monoclonal Antibody [clone: FN50] (APC)

Catalog # MSPP-100-1349

Supplier: STEMCELL Technologies

Catalog # MSPP-100-1349

Supplier: STEMCELL Technologies

Supplier Number: 100-1349

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Specifications

Antigen name:
CD69 (AIM)
Clonality:
Monoclonal
Clone:
FN50
Conjugation:
APC (Allophycocyanin)
Host:
Mouse
Isotype:
IgG1 kappa
Reactivity:
Human
Size:
100 Units
Environmentally Preferable:
Gene ID:
969
Cat. no.:
MSPP-100-1349

Specifications

About this item

Mouse monoclonal antibody against human CD69 (AIM).

B cells
Granulocytes
Subsets
Nk cells
T cells

The monoclonal mouse CD69 antibody reacts with CD69, a gp28/34 disulfide bonded homodimer with a molecular weight of 60 kDa under non-reducing conditions. CD69, also known as the Very Early Activation Antigen, EA-1, Leu23, Activation Inducer Molecule (AIM) and CLEC2C, is a type II transmembrane protein that is constitutively expressed by activated platelets. Use this monoclonal antibody in applications requiring detection of CD69 such as flow cytometry (FC). Studies show that CD69 crosslinking activates various events that lead to platelet activation and aggregation, such as calcium influx, degranulation, and arachidonate metabolism by cyclooxygenase. Upon activation of various lymphocytes, CD69 expression is induced in T cells, thymocytes, B cells, NK cells, neutrophils, and eosinophils, highlighting its role in lymphocyte signal transduction and activation. The protein also plays a role in signal transduction of natural killer cells and platelets. Diseases associated with CD69 dysfunction include coccidiodomycosis and asthma.

Caution: Product restrictions: (i) Customer shall not make products or any portion of them in any way, shape or form, including as a component of another product available for the purpose of further resale or alter or remove the Product label and the Supplier’s mark of origin without express written permission of Supplier and (ii) Customer is familiar with Supplier’s restrictions on the use of the products and shall use the products in compliance with such restrictions and the applicable Supplier Product Information sheet (collectively, the 'Product Restrictions').

Type: Anti-CD69 (AIM) Mouse Monoclonal Antibody [clone: FN50] (APC)
Antigen: CD69 (AIM)
Clonality: Monoclonal
Clone: FN50
Conjugation: APC
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human