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Anti-E-Cadherin (CD324) Mouse Monoclonal Antibody [clone: 7G5D4]
Anti-E-Cadherin (CD324) Mouse Monoclonal Antibody [clone: 7G5D4]
  MSPP-100-1063
 :  STEMCELL Technologies
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Anti-E-Cadherin (CD324) Mouse Monoclonal Antibody [clone: 7G5D4]
  MSPP-100-1063
 :  STEMCELL Technologies
 :  100-1063

 

  • Antigen name:
    E-Cadherin (CD324)
  • Clonality:
    Monoclonal
  • Clone:
    7G5D4
  • Host:
    Mouse
  • Isotype:
    IgG1
  • Reactivity:
    Human
  • Size:
    100 µl
  • Gene ID:
    999
  • Cat. no.:
    MSPP-100-1063

 

 

Mouse monoclonal antibody against human E-cadherin (CD324).

  • Intestinal cells

Clone 7G5D4 is a mouse monoclonal antibody that reacts with human E-cadherin (CD324), a transmembrane glycoprotein present in the adherens junction of epithelial cells. E-cadherin consists of a large extracellular domain composed of five cadherin-motif subdomains, a single-pass transmembrane segment, and a short conserved cytoplasmic domain. Use this polyclonal antibody in applications requiring detection of E-cadherin. It is verified for use with immunocytochemistry (ICC) and immunofluorescence (IF). E-cadherin is a calcium dependent cell-cell adhesion protein that plays a central role in the growth and development of cells by controlling tissue architecture and maintaining tissue integrity. It consists of a large extracellular domain composed of five cadherin-motif subdomains, a single-pass transmembrane segment, and a short conserved cytoplasmic domain. As a key regulator of epithelial junction formation, E-cadherin associates with catenins and is necessary for cell-cell adhesion. The E-cadherin-catenin complex is associated with cortical actin bundles at both the zonula adherens and the lateral adhesion plaques. Disruption of this complex by tyrosine phosphorylation results in changes to cell adhesion properties. The expression of E-cadherin has been suggested in tumor metastasis.

 : Product restrictions: (i) Customer shall not make products or any portion of them in any way, shape or form, including as a component of another product available for the purpose of further resale or alter or remove the Product label and the Supplier’s mark of origin without express written permission of Supplier and (ii) Customer is familiar with Supplier’s restrictions on the use of the products and shall use the products in compliance with such restrictions and the applicable Supplier Product Information sheet (collectively, the 'Product Restrictions').

Type: Anti-E-Cadherin (CD324) Mouse Monoclonal Antibody [clone: 7G5D4]
Antigen: E-Cadherin (CD324)
Clonality: Monoclonal
Clone: 7G5D4
Conjugation:
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human