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QuantiFluo™ Urokinase Inhibitor Screening Assay Kit
  77441-672
 :  
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QuantiFluo™ Urokinase Inhibitor Screening Assay Kit
  77441-672
 :  DUKI-100
 :  

 

  • Description:
    QuantiFluo™ Urokinase inhibitor screening assay kit
  • Size:
    100 tests
  • Cat. no.:
    77441-672

 

 

For evaluation of drugs and screening potential inhibitors of urokinase.

  • Safe
  • Non-radioactive assay
  • Fast
  • Assay is completed within a 30 minutes reaction time
  • Homogeneous 'mix-incubate-measure' type assay
  • Can be readily automated to assay thousands of samples per day

UROKINASE PLASMINOGEN ACTIVATOR (urokinase, uPA) is a key serine protease involved in the degradation of the extracellular matrix that catalyzes the conversion of plasminogen to active plasmin. It acts as a thrombolytic agent to break up blood clots and when over-expressed, has been reported to influence the growth of certain malignant tumors (breast, prostate, etc.). BioAssay Systems’ DUKI-100 Kit provides a convenient fluorimetric means to screen for potential urokinase inhibitors. In this assay, the fluorimetric substrate reacts with urokinase and an inhibitor will decrease the fluorescence at λex/em = 380/450 nm.