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Specifications
- Antibody type:Primary
- Antigen name:S100B/S100 beta
- Clonality:Polyclonal
- Gene ID:6285
- Host:Rabbit
- Isotype:IgG (H, L)
- Reactivity:Chicken,Human,Bovine,Rat,Mouse
- Conjugation:Unconjugated
- Flow cytometry:Yes
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Size:100 µl
- Storage buffer:0.01 M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% glycerol
- Storage temperature:Store at –20 °C for 12 months.
- Concentration:1 µg/µl
- Purification:Purified by Protein A
- Packaging:Vial
Specifications
About this item
S100 beta is a member of the S100 family of proteins containing 2 EF-hand calcium binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.
Type: Primary
Antigen: S100B/S100 beta
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG (H, L)
Reactivity: Human, Mouse, Rat, Bovine, Chicken