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NHDC - Human Dendritic Cells
NHDC - Human Dendritic Cells
Catalog # CA10064-282
CAS Number:  
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NHDC - Human Dendritic Cells
Catalog # CA10064-282
Supplier Number:  CC-2701
CAS Number:  

Specifications

  • Description:
    NHDC - Human dendritic cells
  • Size:
    2.5 million cells
  • Cat. no.:
    CA10064-282

Specifications

About this item

Dendritic Cells (DCs) act as the messenger cells of the immune system by processing antigens from pathogens and presenting the antigens to T cells to initiate an immune response.

  • All cells test negative for mycoplasma, bacteria, yeast, and fungi
  • HIV-1, Hepatitis B and Hepatitis C are not detected for all donors and/or cell lots

Poietics® Normal Human Dendritic Cells are tested for a panel of specific surface markers, including CD11c+, CD86+, CD80+. HLADR+, and CD14- to provide detailed characterization of the cells. These cells can survive up to 7 days in culture with the proper cytokines (IL-4 and GM-CSF) to maintain the cells as immature dendritic cells (iDCs). Cells can be further differentiated to mature dendritic cells with the addition of TNF-α and IL-1β.

Applications: Antigen presentation and uptake Primary Research Pharmacology Drug-induced immunosuppression of cytokine secretion.

Cryopreserved Poietics® Normal Human Dendritic Cells (NHDC) are guaranteed to contain ≥3 million viable cells per ampoule. Expression levels are tested for CD80, CD86, HLA-DR, CD11c, and CD14 and provided for information only. HIV-1, hepatitis B and hepatitis C are not detected for all donors and/or cell lots. A Certificate of Analysis is provided for each cell lot purchased. Recommended Medium: LGM-3® Lymphocyte Growth Medium + 50 ng/ml GM-CSF + 50 ng/ml IL-4.

Delivery: Content: 1× Cryopreserved ampule of NHDC containing ≥2.5 million cells. Certificate of Analysis provided for every cell lot.