Anti-EDC4 Rabbit Polyclonal Antibody
- Item requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.
- Return Policy
Product Details & Documents
The major eukaryotic mRNA decay pathway occurs through deadenylation, decapping, and 5' to 3' degradation of the mRNA. Decapping is a critical control point in this decay pathway. Edc4 (enhancer of mRNA decapping 4), also known as human enhancer of decapping large subunit (HEDLS), RCD-8 or Ge-1, is a 1,401 amino acid protein belonging to the WD repeat EDC4 family that is involved in mRNA decapping during mRNA degradation. As part of the mRNA degradation process, Edc4 becomes part of a complex that also contains hDcp1a, hDcp2a, RCK and Edc3. Localizing to P-body and cytoplasm, Edc4 contains a nuclear localization sequence (NLS) which enables it to selectively enter the nucleus as well. Edc4 becomes phosphorylated upon DNA damage and exists as two alternatively spliced isoforms that are encoded by a gene that maps to human chromosome 16q22.1.
Type: Primary
Antigen: EDC4
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG (H, L)
Reactivity: Human, Mouse, Rat
Specifications
- Size:100 µl
- Packaging:Vial
- Clonality:Polyclonal
- Flow cytometry:Yes
- Purification:Purified by protein A
- Antibody type:Primary
- ImmunoFluorescence:Yes
- Isotype:IgG (H, L)
- Storage temperature:Shipped at 4 ℃. Store at −20 °C for one year. Avoid repeated freeze/thaw cycles.
- Host:Rabbit
- Concentration:1 µg/µl
- Molecular weight:151
- Antigen name:EDC4
- Cat. No.:77436-856
- Reactivity:Human|Rat|Mouse
- Gene ID:23644
- ImmunoChemistry:Yes
- Conjugation:Unconjugated
- Storage buffer:0.01 M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% glycerol
- ELISA:Yes
Recommendations will be personalized based on your shopping preferences only if you have given your consent by enabling "Enhance my Shopping Experience" on the "Personal Info page".
Otherwise, you will receive generic recommendations.
Catalog #: CA21905-026
Supplier: Kimberly-Clark