Cryopreserved HUVECs are shipped as frozen primaries. They are guaranteed through 15* population doublings (*except HUVEC-XL® guaranteed through 5 PD), express CD31/105, von Williebrand Factor VIII, and are positive for acetylated low density lipoprotein uptake.

• Guaranteed through 15 population doublings
• All cells test negative for mycoplasma, bacteria, yeast, and fungi
• HIV-1, Hepatitis B and Hepatitis C are not detected for all donors and/or cell lots

All cells test negative for mycoplasma, bacteria, yeast, and fungi. HIV-1, hepatitis B and hepatitis C are not detected for all donors and/or cell lots. Our pooled vs. single donor options allow researchers to study or exclude donor variability from their experiments. Depending upon the study, pooled version is typically utilized to reduce donor variability while single donor option allows researchers to assess donor-specific differences.

HUVEC-XL size consists of 10 million cells/amp achieved by pooling donors. This option is designed to support studies that require large volume of cells while still offering cost-benefits to researchers.

Suitable HUVECs for research:
C2517AS (single donor), C2519AS (pooled donor) - Pre-screened HUVECs in EGM®-2 media. Screened for angiogenesis markers and test positive for expression of eNOS, Axl, Tie-2 and VEGFr2
C2517A (single donor), C2519A (pooled donor), 00191027 (XL size) - Isolated in EGM®-2 media, in presence of growth factors such as VEGF, rhFGF, rhEGF, and others. Does not contain BBE
CC-2517 (single donor), CC-2519 (pooled donor) - Both isolated in EGM® media, in absence of defined growth factors. Contains BBE. No exogenous VEGF.
CC-2935 (single donor) - Isolated in EGM® - Plus media: Improved version of part number CC-2517. Offers faster proliferation rates than HUVEC isolated in EGM® media. No exogenous VEGF.

Applications: Would healing, angiogenesis, tissue engineering, inflammation, oncology, pharmacology, vascular modeling, transfection.