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- Antibody type:Primary
- Antigen name:CTH
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 680
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Western blot:Yes
- Size:100 µl
- Environmentally Preferable:
- Epitope:51-150/405
- Form:Liquid
- Gene ID:1491
- Antigen synonyms:Cystathionase|CGL_HUMAN|Homoserine deaminase|Homoserine dehydratase|MGC9471|CTH|Gamma-cystathionase|Cystathionine gamma-lyase|Cystathionine gamma lyase|Gamma cystathionase|Cysteine desulfhydrase|CSE
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0.01 M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- Storage temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human Cystathionine gamma lyase
- Purification:Purified by Protein A
- Cat. no.:76110-722
- Packaging:Vial
Catalyzes the last step in the transsulfuration pathway from methionine to cysteine. Has broad substrate specificity. Converts cystathionine to cysteine, ammonia and 2-oxobutanoate. Converts two cysteine molecules to lanthionine and hydrogen sulfide. Can also accept homocysteine as substrate. Specificity depends on the levels of the endogenous substrates. Generates the endogenous signaling molecule hydrogen sulfide (H2S), and so contributes to the regulation of blood pressure. Defects in CTH are the cause of cystathioninuria (CSTNU). It is an autosomal recessive phenotype characterized by abnormal accumulation of plasma cystathionine, leading to increased urinary excretion.
Type: Primary
Antigen: CTH
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 51-150/405
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat