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Specifications
- Antibody type:Primary
- Antigen name:SMARCD3
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 750
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Western blot:Yes
- Size:100 µl
- Environmentally Preferable:
- Epitope:101-200/483
- Form:Liquid
- Gene ID:6604
- Antigen synonyms:Smarcd3|SMRD3_HUMAN|SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily d member 3|60 kDa BRG-1/Brm-associated factor subunit C|CRACD3|BRG1-associated factor 60C|BAF60C|BRG1 associated factor 60C|Rsc6p|MGC111010|60 kDa BRG 1/Brm associated factor subunit C|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0.01 M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- Storage temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human SMARCD3
- Purification:Purified by Protein A
- Cat. no.:76110-708
- Packaging:Vial
Specifications
About this item
SMARCD3, is a member of the SMARCD family and contains one SWIB domain. Two isoforms, isoform 1 and isoform 2 exist due to alternative splicing events. Both isoforms are expressed in placenta, salivary gland, kidney, brain, trachea, uterus, prostate, testis, thyroid, spleen and heart, while isoform 1 is also expressed in adipose tissue and skeletal muscle. Localizing to the nucleus, SMARCD3 is a component of the ATP-dependent chromatin remodeling complex SNF/SWI and is believed to play a role in nucleosome remodeling. SMARCD3 also plays an important role in the regulation of muscle development. In mice, the silencing of the gene en-coding SMARCD3 leads to defects in heart morphogenesis. In addition, both isoforms of SMARCD3 directly interact with and function as coactivators for several transcription factors.
Type: Primary
Antigen: SMARCD3
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 101-200/483
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat