Difco TC Yeastolate, ultra-filtered (UF), is an animal origin-free (AOF) product derived from water-soluble portions of autolyzed yeast (Saccharomyces cerevisiae). This product is intended as a nutritional supplement for bacterial, insect, and mammalian cell culture.

• Mixture of low molecular weight peptides, amino acids, carbohydrates (simple and complex), as well as vitamins
• Meets additional requirements for reduced endotoxin, clarity, and suitability for the biopharmaceutical industry
• Ultra-filtered
• Supplementation of TC yeastolate to CHO cell culture can enhance growth and mAb production

These products are intended as nutritional supplements for bacterial, insect, and mammalian cell culture. TC yeastolate has been used in insect cell culture. TC yeastolate was found to be a very versatile supplement to enhance growth and production characteristics of Sf9 and Gibco™ High Five™ cells [1-5]. Additionally, supplementation of TC yeastolate to CHO cell culture can enhance growth and mAb production.