Permethylated ß-cyclodextrin chiral stationary phase that resolves volatile optical isomers.

• ß-cyclodextrin in (35%-Phenyl)-methylpolysiloxane
• Permethylated ß-cyclodextrin
• Chiral separations without chiral-specific derivatization
• Phenyl-based polymer provides low bleed and does not interfere with nitrogen-specific detectors
• Available in two concentrations of ß-cyclodextrin: 10% and 20%
• 20% ß-cyclodextrin is the best choice for initial screening
• Tested with the tightest industry QC specifications for column bleed, sensitivity, and efficiency

Agilent J&W HP-Chiral ß has a chiral stationary phase based on permethylated ß-cyclodextrin, which is broadly applicable for resolving volatile optical isomers. ß-cyclodextrin is dispersed in a phenyl-based polymer, which provides low bleed and will not interfere with nitrogen-specific detectors such as the nitrogen phosphorus (NPD) detector, allowing optimized sensitivity for chiral compounds containing nitrogen.