A high fidelity restriction endonuclease that recognizes the sequence T^GATCA. High Fidelity (HF) Restriction Enzymes have 100% activity in CutSmart Buffer; single-buffer simplicity means more straightforward and streamlined sample processing.

• Engineered for improved performance
• 100% activity in CutSmart Buffer (over 215 enzymes are available in the same buffer)
• Reduced star activity

HF enzymes are all Time-Saver qualified and can therefore cut substrate DNA in 5 to 15 with the flexibility to digest overnight without degradation to DNA. Engineered with performance in mind, HF restriction enzymes are fully active under a broader range of conditions, minimizing off-target products, while offering flexibility in experimental design.