Native silica is generally regarded as the most polar SPE sorbent available. Bond Elut SI is particularly effective at separating compounds with a very similar structure.

• Highly polar phase retains polar molecules from nonpolar matrices
• High purity silica
• Separate compounds with very similar structures

Native silica is generally regarded as the most polar SPE sorbent available. Bond Elut SI is particularly effective at separating compounds with a very similar structure. Applying the analytes in a non-polar solvent, then increasing the solvent polarity by increasing the concentration of a polar modifier, such as THF or ethyl acetate, delivers effective separations.