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Specifications
- Conjugation:Unconjugated
- Protein/peptide type:Recombinant
- Source:E. coli
- Species:Mouse
- Size:50 µg
- Biological activity:Assay #1: Determined by its ability to chemoattract IL-2 activated T cells using a concentration range of 0.1-10.0 ng/ml. Assay #2: Determined by its ability to chemoattract CXCR3-transfected HEK293 cells using a concentration range of 100-500 ng/ml.
- Gene ID:15945
- Animal-free:Y
- Protein synonyms:gamma-Interferon Inducible Protein-10|CXCL10|crg-2
- Protein/peptide name:IP-10 (CXCL10)
- Purity:98%
- Molecular weight:8.7 kDa
- Sequence:IPLARTVRCN CIHIDDGPVR MRAIGKLEII PASLSCPRVE IIATMKKNDE QRCLNPESKT IKNLMKAFSQ KRSKRAP
- Endotoxin level:Low
- Formulation:Lyophilized
- Shipping temperature:Ambient
- Cat. no.:76303-822
Specifications
About this item
IP-10 is a CXC chemokine that signals through the CXCR3 receptor. IP-10 selectively chemoattracts Th1 lymphocytes and monocytes, and inhibits cytokine-stimulated hematopoietic progenitor cell proliferation. Additionally, it is angiostatic and mitogenic for vascular smooth muscle cells. Recombinant Murine IP-10 is an 8.7 kDa protein consisting of 77 amino acids, including the four conserved cysteine residues present in CXC chemokines.