To order chemicals, medical devices, or other restricted products please provide ID that includes your business name & shipping address via email [email protected] or fax 484.881.5997 referencing your VWR account number. Acceptable forms of ID are:
- • State issued document with your organization's Federal Tax ID Number
- • State issued document with your organization's Resale Tax ID Number
- • City or County issued Business License
- • State Department of Health Services License
- • Any other ID issued by the State that includes the business name & address
* ATTN: California Customers may require additional documentation as part of the CA Health & Safety Code. Products that fall under this regulation will be placed on a mandatory 21-day hold after documentation is received. VWR will not lift restrictions for residential shipping addresses.
Specifications
- Antibody type:Primary
- Clonality:Polyclonal
- Host:Rabbit
- Antigen symbol:PKM
- ELISA:Yes
- Size:100 µg
- Western blot:Yes
- Shipping temperature:Dry Ice
- Purification:Affinity purified
- Cat. no.:76262-730
Specifications
About this item
Anti-PKM2 Antibody was designed, produced, and validated as part of the Joy Cappel Young Investigator Award (JCYIA). Pyruvate kinase has been shown to be expressed in tumor, embryonic and normal proliferating cells in varying levels. Studies show that when PKM2 is secreted it can induce EGFR phosphorylation which stimulates the EGFR downstream pathway. Previously PKM has been shown to be critical for aerobic glycolysis. Four isoforms of PKM play alternative roles within the system and post-translational modifications along these isoforms induce multiple pathways making this Anti-PKM2 antibody ideal for investigators involved in cancer research and post-translational modifications.
This affinity purified antibody has been tested for use in western blot. Specific conditions for reactivity should be optimized by the end user. Expect a band 56-58 kDa in size corresponding to PKM2 by western blotting in the appropriate cell lysate or extract.
Type: Primary
Antigen: PKM
Clonality: Polyclonal
Clone:
Conjugation:
Epitope:
Host: Rabbit
Isotype:
Reactivity: