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Specifications
- Antibody type:Primary
- Clonality:Monoclonal
- Clone:7H10.D3.D4.G5
- Host:Mouse
- Isotype:IgG1 kappa
- Antigen symbol:PAX6
- ELISA:Yes
- ImmunoFluorescence:Yes
- Size:25 µL
- Western blot:Yes
- Shipping temperature:Dry Ice
- Purification:Protein A purified
- Cat. no.:76235-004
Specifications
About this item
Paired box protein Pax-6 also known as aniridia type II protein (AN2) or oculorhombin is a transcription factor with key functions in the development of the eye, nose, central nervous system and pancreas. Pax6 further seems to be required for the differentiation of pancreatic islet alpha cells. PAX6 has been shown to bind to a promoter element in the glucagon, insulin and somatostatin promoters and regulates the specification of the ventral neuron subtypes by establishing the correct progenitor domains. Isoform 5a appears to function as a molecular switch that specifies target genes.
Anti-PAX6 antibody is ideal for researchers interested in developmental biology, stem cell research, cell growth and cancer research.
Anti-PAX6 antibody is suitable for ELISA and Immunofluorescence. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 46.7 kDa in size corresponding to PAX6 by western blotting in the appropriate cell lysate or extract.
Type: Primary
Antigen: PAX6
Clonality: Monoclonal
Clone: 7H10.D3.D4.G5
Conjugation:
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: