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Specifications
- Antibody type:Primary
- Antigen name:IL1R2
- Clonality:Polyclonal
- Host:Rabbit
- Antigen symbol:IL1R2
- ELISA:Yes
- ImmunoPrecipitation:Yes
- Size:100 µL
- Western blot:Yes
- Storage temperature:Store vial at –20 °C. Aliquot contents and freeze at –20 °C. Centrifuge product if not completely clear after standing at room temperature. Stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use.
- Shipping temperature:Dry Ice
- Cat. no.:76234-800
Specifications
About this item
Interleukin-1 Receptor Type 2 (IL-1RII) ins a non-signaling receptor for IL1A, IL1B and IL1RN and reduces IL1B activities. It serves as a decoy receptor by competitive binding to IL1B and preventing its binding to IL1R1. It also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.
This antiserum against Human IL-1 Receptor Type II (IL-1RII) has been tested for use in ELISA, radioimmunoassays and immunoprecipitation. Reactivity in other immunoassays is unknown. IL-1RII has been termed p68 or CD121 in some laboratories. IL-1RII has been shown to bind IL-1, IL-1a and IL-1b.
Type: Primary
Antigen: IL1R2
Clonality: Polyclonal
Clone:
Conjugation:
Epitope:
Host: Rabbit
Isotype:
Reactivity: