About this item
This MAb recognizes a 27 kDa protein, identified as the p27Kip1, a cell cycle regulatory mitotic inhibitor. It is highly specific and shows no cross-reaction with other related mitotic inhibitors. p27Kip1 functions as a negative regulator of G1 progression and has been proposed to function as a possible mediator of TGF- induced G1 arrest. p27Kip1 is a candidate tumor suppressor gene. This MAb is excellent for staining of formalin-fixed tissues.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.
Type: Primary
Antigen: CDKN1B
Clonality: Monoclonal
Clone: Clone KIP1/769
Conjugation: CF488A
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human, Monkey, Mouse, Rat
To order chemicals, medical devices, or other restricted products, please provide identification that includes your business name and shipping address via email [email protected] or fax 484.881.5997 referencing your VWR account number. Acceptable forms of identification are:
- • Issued document with your organization's Federal Tax ID Number
- • Government issued document with your organization's Resale Tax ID Number
- • Any other Government ID that includes the business name and address
Avantor will not lift restrictions for residential shipping addresses.
Specifications
- Catalog No:
- 75967-334
- 75967-332
- Antigen symbol:
- CDKN1B
- CDKN1B
- Antigen name:
- p27 / KIP1
- p27 / KIP1
- Antibody type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Conjugation:
- CF® 488A
- CF® 488A
- Clone:
- KIP1/769
- KIP1/769
- Reactivity:
- Monkey, Human, Rat, Mouse
- Monkey, Human, Rat, Mouse
- Host:
- Mouse
- Mouse
- Gene ID:
- Unigene ID: 238990
- Unigene ID: 238990
- Isotype:
- IgG1 kappa
- IgG1 kappa
- Western blot:
- Yes
- Yes
- ImmunoChemistry:
- Yes
- Yes
- ImmunoFluorescence:
- Yes
- Yes
- Concentration:
- 0.1 mg/mL
- 0.1 mg/mL
- Storage buffer:
- PBS/0.1% BSA/0.05% azide
- PBS/0.1% BSA/0.05% azide
Specifications
Supplier: BDH
Supplier: VWR International
Supplier: VWR International
Supplier: VWR International
Supplier: Corning
Supplier: VWR International