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- Antibody type:Primary
- Antigen name:MART-1 / Melan-A
- Antigen symbol:MLANA
- Clonality:Monoclonal
- Clone:M2-7C10 M2-9E3 A103
- Conjugation:Unconjugated
- Host:Mouse
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:
- Reactivity:Human,Dog,Rat,Mouse
- Western blot:Yes
- Size:50 μL
- Environmentally Preferable:
- Gene ID:Unigene ID: 154069
- Storage buffer:PBS, no BSA, no azide
- Concentration:1 mg/mL
- Cat. no.:75959-818
- Supplier No.:BNUM0700-50
This antibody recognizes a protein doublet of 20-22 kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This MAb cocktail labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.
Type: Primary
Antigen: MLANA
Clonality: Monoclonal
Clone: Clone M2-7C10 M2-9E3 A103
Conjugation: Unconjugated, BSA-and azide-free
Epitope:
Host: Mouse
Isotype: IgGs
Reactivity: Dog, Human, Mouse, Rat