About this item
CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®647 is a far-red fluorescent dye (Ex/Em 650/665 nm) with excellent brightness. It also is compatible with super-resolution imaging by STORM.
Type: Primary
Antigen: CD6
Clonality: Monoclonal
Clone: Clone 3F7B5
Conjugation: CF647
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human
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Specifications
- Catalog No:
- 75917-104
- 75916-516
- Antigen symbol:
- CD6
- CD6
- Antigen name:
- CD6
- CD6
- Antibody type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Conjugation:
- CF® 647
- CF® 647
- Clone:
- 3F7B5
- 3F7B5
- Reactivity:
- Human
- Human
- Host:
- Mouse
- Mouse
- Gene ID:
- Unigene ID: 744366
- Unigene ID: 744366
- Isotype:
- IgG1
- IgG1
- ImmunoChemistry:
- Yes
- Yes
- ImmunoFluorescence:
- Yes
- Yes
- Concentration:
- 0.1 mg/mL
- 0.1 mg/mL
- Storage buffer:
- PBS/0.1% BSA/0.05% azide
- PBS/0.1% BSA/0.05% azide