IGFBP-6 ELISA is for the measurement of human IGFBP-6 in human serum/plasma and other body fluids.

• Dynamic Range: 0.1 - 10 ng/ml
• Sensitivity: 0.026 ng/mL
• Incubation: 3 hours

The Insulin-like Growth Factor 6 (IGFBP-6) is part of the IGF-System which consists of several binding proteins (1-6) and IGF-I and –II. The Insulin-like Growth Factors are involved in the control of human growth and regulated themselves by their binding proteins. The IGFBPs show high amino acid sequence homology, they have conserved N- and C-terminal domains which are involved in IGF-binding. In contrast the central linker region is highly variable. This region is not directly involved in IGF-binding but influences stability and localisation of the IGFBP / IGF complex and can be modified by glycosylation and phosphorylation.