Human PYY ELISA determines human PYY [both PYY (3-36) and PYY (1-36)] in serum and plasma.

• Dynamic Range: 0.082 - 20 ng/mL
• Sensitivity: 0.082 ng/mL
• Incubation: 24 hours

This Eagle Biosciences Human PYY ELISA is an enzyme immunoassay (EIA) kit and is a stable and convenient assay system for human peptide YY (PYY). PYY was isolated initially by Tatemoto et al. (1980) from the extract of pig duodenum and shown to be a polypeptide consisting of 36 amino acids residues. PYY is homologous to pancreatic polypeptide (PP) and neuropeptide Y (NPY). PYY is localized mainly in Endocrinology cells in the intestine (ileum, colon, and rectum). PYY shows an inhibitory action on contraction of the gastrointestinal tract and on secretion of pancreatic and gastric juice. PYY is released by taking diet. The PYY level in human blood decreases after resection of the intestine, possibly be due to the decrease in number of the Endocrinology cells secreting PYY. The Human PYY ELISA Assay kit is prepared by using synthetic human PYY (3-36) as standard and biotinylated human PYY (3-36) as labeled Antigens. The kit can be used for measurement of PYY [both PYY (3-36) and PYY (1-36)] in human serum or plasma with high sensitivity. It will be a specifically useful tool for PYY research.