Total Antibodies to Infliximab EIA detects total antibodies to Infliximab in serum & plasma samples.

• Dynamic Range: 10 tAU/mL
• Sensitivity: Cut-off
• Incubation: 1.5 hours

The drug Infliximab (trade name Remicade® and Remsima®) is a chimeric monoclonal antibody and used to treat auto-immune disorders. One of the major concerns, despite of its wide usage, is the potential development of anti-Infliximab antibodies (ATI) which in turn may interfere with the drug efficacy as mainly judged by observing the relapse of signs and symptoms of disease and necessitate dose-escalation or potentially ending up the treatment.The ImmunoGuide Total Antibody to Infliximab ELISA Kit can be efficiently used for measuring free and Infliximab-bound antibodies against the drug Infliximab. In combination with the drug level determination, the Total Antibody to Infliximab ELISA Kit has been designed for the measurement of free antibodies against this drug. It also detects such antibodies which already are bound to the drug, even if the drug is present in a 20 fold excess.