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Specifications
- Size:500 Assays (96-well plate) or 1250 Assays (384-well)
- Cat. no.:103010-398
- Storage Temperature:– 20 °C
- Includes:The assays can be performed in a convenient 96-well microplate format, kit includes essential components and detailed protocol and references
- Supplier No.:AS-72079
Specifications
About this item
West Nile virus (WNV) causes severe neurological disease and fatalities in both human and animal hosts
The SensoLyte® 440 West Nile Virus Protease Assay Kit provides a convenient homogenous assay for high throughput screening of WNV protease inhibitors and for continuous assay of NS3 protease activity using a fluorogenic Pyr-RTKR-AMC peptide. Upon NS3 protease cleavage, Pyr-RTKR-AMC generates the AMC fluorophore that has bright blue fluorescence and can be detected at excitation/emission=354 nm/442 nm.
There is currently no effective vaccine or antiviral drug to protect against WNV infection. The West Nile virus NS3 protease, essential for the proteolytic processing of the viral polyprotein precursor, is a promising target for the development of anti-WNV drugs.