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Specifications
- Conjugation:Mca-DNP
- Size:1 mg
- Storage conditions:–20 °C
- Protein synonyms:MMP FRET|MMP Substrate V|Matrix Metalloproteinase substrate V
- Protein/peptide name:390 MMP FRET Substrate V
- Purity:95%
- Molecular weight:1193.2 Da
- Sequence:Mca-PLGLEEA-Dap(Dnp)-NH2
- Cat. no.:103007-144
- Supplier No.:AS-62027
Specifications
About this item
Matrix Metalloproteinases (MMPs) are a large family of endopeptidases. Collectively, MMPs can degrade all kinds of extracellular matrix proteins, and can also process a number of bioactive molecules. They are known to be involved in the cleavage of cell surface receptors, the release of apoptotic ligands, and chemokine/cytokine inactivation. MMPs are also thought to play a major role in cell behaviors such as cell proliferation, migration (adhesion/dispersion), differentiation, angiogenesis, apoptosis, and host defense.
This peptide is a substrate for the MMP-12, macrophage elastase, Abs/Em = 325/393 nm. MMPs are considered to be critical mediators of both normal and pathological tissue remodeling processes.
Sequence:Mca-PLGLEEA-Dap(Dnp)-NH2
MW:1193.2 Da
% peak area by HPLC:95
Storage condition:-20° C