Some Products May Appear Restricted
To ensure a smooth and speedy checkout, please log in to your account. Some items may show as restricted simply because you're not logged in.
If you do not have an account, you can register using our registration webform (https://www.avantorsciences.com/ca/en/login/register)
If you're still seeing restrictions after logging in, certain products—like chemicals or medical devices—require additional account verification steps to be able to place an order. Some items may additionally require a specific license or customer documentation; additional documentation will be requested for these items prior to shipment.
Specifications
- Conjugation:Unconjugated
- Size:1 mg
- Storage conditions:–20 °C
- Protein synonyms:Cell-permeable NEMO Peptide|NEMO binding Peptide|NBD Peptide
- Protein/peptide name:IKKgamma NEMO Binding Domain (NBD) Inhibitory Peptide
- Purity:95%
- Molecular weight:3693.3 Da
- Sequence:DRQIKIWFQNRRMKWKKTALDWSWLQTE
- Cat. no.:103006-380
- Supplier No.:AS-61169
Specifications
About this item
A cell-permeable synthetic peptide NEMO-binding domain peptide (NBD peptide) corresponding to the NEMO amino-terminal alpha-helical region is shown to block TNF-alpha-induced NF-kB activation. The interaction of IKgammaNEMO with the IKK complex is critical for the activation of the IKK complex and the subsequent activation of NF-kB.
Sequence:DRQIKIWFQNRRMKWKKTALDWSWLQTE
MW:3693.3 Da
% peak area by HPLC:95
Storage condition:-20° C