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Specifications
- Conjugation:Unconjugated
- Source:E. coli
- Size:50 µg
- Storage conditions:–80 °C
- Form:Liquid
- Shipping conditions:–80 °C, dry ice
- Enzyme name:NAD Nucleotidase
- Enzyme activity:With AMP: 856.4 nmol of Ade/min/mg of protein
With NMN: 110,3 nmol of NR/min/mg of protein
With NAD: 5.4 nmol of Ade/min per mg of protein | 5.3 nmol of NR/min/mg of protein - Purity:98%
- Molecular weight:~63.0 kDa
- Concentration:0.5 mg/ml (Lot specific)
- Formulation:In 5mM KH2PO4, pH 6.8 containing 100 mM TRIS-HCl (pH 8.5) and 10 mM MgCl₂.
- Cat. no.:102980-456
- Supplier No.:AG40T0110C050
Specifications
About this item
NadN (NAD nucleotidase) is a periplasmic enzyme from Haemophilus influenzae, a major pathogen of the respiratory tract in humans that has developed the capability to exploit host NAD(P) for its nicotinamide dinucleotide requirement
- UniProt link Q4QNY4: NAD Nucleotidase (H. influenza)
NadN plays a central role by degrading NAD into adenosine and NR (nicotinamide riboside), NMN to nicotinamide riboside and AMP to adenosine. It shows a broad substrate specificity, recognizing either mono- or di-nucleotide nicotinamides and different adenosine phosphates with a maximal activity on 5'-adenosine monophosphate. It can be used as an economically alternative to produce NR (nicotinamide riboside). Catalytic activity: NAD=AMP + NMN=Ade+NR+PPi | AMP=Ade+Pi | NMN=NR+Pi