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NAD Kinase (from E. coli)
NAD Kinase (from E. coli)
Catalog # 102980-450
Supplier:  Adipogen
CAS Number:  
NAD Kinase (from E. coli)
Catalog # 102980-450
Supplier:  Adipogen
Supplier Number:  AG-40T-0107-C050
CAS Number:  

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Specifications

  • Conjugation:
    Unconjugated
  • Source:
    E. coli
  • Size:
    50 µg
  • Storage conditions:
    –80 °C
  • Form:
    Liquid
  • Shipping conditions:
    –80 °C, dry ice
  • Enzyme name:
    NAD Kinase
  • Enzyme activity:
    ~1.2 U/mg protein. (Substrate: NAD (+ ATP))
    ~3.8 U/mg protein. (Substrate: NAD (+ poly(P))
    One unit is defined as the amount of enzyme that synthesizes 1µmol nicotinamide adenine dinucleotide phosphate (NADP) per min.
  • Purity:
    98%
  • Molecular weight:
    ~33.0 kDa
  • Concentration:
    0.5 mg/ml (Lot specific)
  • Formulation:
    In 10 mM TRIS at pH 8.0, containing 1 mM MgCl₂, 0.5 mM EDTA, 1 mM DTT and 1 mM PMSF.
  • Cat. no.:
    102980-450
  • Supplier No.:
    AG40T0107C050

Specifications

About this item

NAD kinase catalyzes the transfer of a phosphate group from ATP to NAD+ to generate NADP+, which in its reduced form acts as an electron donor for biosynthetic reactions

  • UniProt link P0A5S6: NAD Kinase (M. tuberculosis)

NADP+ is an essential coenzyme in metabolism and provides reducing power to biosynthetic processes such as fatty acid biosynthesis. NAD kinase from Mycobacterium tuberculosis is not ATP-dependent but has a broader substrate specificity than human NAD kinase. It can economically produce NADP+ by using other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus. Was identified as a high-confidence drug target. Catalytic activity: ATP + NAD+ = ADP + NADP+