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Specifications
- Conjugation:Unconjugated
- Source:E. coli
- Size:50 µg
- Storage conditions:–80 °C
- Form:Liquid
- Shipping conditions:–80 °C, dry ice
- Enzyme name:NAD Kinase
- Enzyme activity:~1.2 U/mg protein. (Substrate: NAD (+ ATP))
~3.8 U/mg protein. (Substrate: NAD (+ poly(P))
One unit is defined as the amount of enzyme that synthesizes 1µmol nicotinamide adenine dinucleotide phosphate (NADP) per min. - Purity:98%
- Molecular weight:~33.0 kDa
- Concentration:0.5 mg/ml (Lot specific)
- Formulation:In 10 mM TRIS at pH 8.0, containing 1 mM MgCl₂, 0.5 mM EDTA, 1 mM DTT and 1 mM PMSF.
- Cat. no.:102980-450
- Supplier No.:AG40T0107C050
Specifications
About this item
NAD kinase catalyzes the transfer of a phosphate group from ATP to NAD+ to generate NADP+, which in its reduced form acts as an electron donor for biosynthetic reactions
- UniProt link P0A5S6: NAD Kinase (M. tuberculosis)
NADP+ is an essential coenzyme in metabolism and provides reducing power to biosynthetic processes such as fatty acid biosynthesis. NAD kinase from Mycobacterium tuberculosis is not ATP-dependent but has a broader substrate specificity than human NAD kinase. It can economically produce NADP+ by using other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus. Was identified as a high-confidence drug target. Catalytic activity: ATP + NAD+ = ADP + NADP+