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- Conjugation:Unconjugated
- Source:E. coli
- Size:50 µg
- Storage conditions:–80 °C
- Form:Liquid
- Shipping conditions:–80 °C, dry ice
- Enzyme name:3-Hydroxykynurenine Transaminase
- Enzyme activity:Specific activity towards D,L-3HK: 33 µmol/min per mg. Primarily catalyses the pyridoxal 5'-phosphate (PLP)-dependent irreversible transamination of 3-hydroxykynurenine (3-HK) to xanthurenic acid (XA).
- Purity:99%
- Molecular weight:~44.3 kDa
- Concentration:0.5 mg/ml (Lot specific)
- Formulation:In 20mM TRIS-HCl pH 8.0, containing 150mM NaCl and 40µM pyridoxal 5'-phosphate (PLP).
- Cat. no.:102980-436
- Supplier No.:AG40T0100C050
The 3-hydroxykynurenine transaminase (3-HKT) gene plays a vital role in the development of malaria parasites by participating in the synthesis of xanthurenic acid, which is involved in the exflagellation of microgametocytes in the midgut of malaria vector species
- UniProt link Q7PRG3: 3-HKT (Anopheles gambiae)
The 3-HKT enzyme is involved in the tryptophan metabolism of Anophelines. The gene had been studied in the important global malaria vector, Anopheles gambiae.