About this item
Interleukin-22 (IL-22), also known as IL-10 related T cell derived inducible factor (ILTIF) was initially identified as a gene induced by IL-9 in mouse T cells and mast cells. IL-22 has been shown to activate STAT1 and STAT3 in several hepatoma cell lines and upregulate the production of acute phase proteins. IL-22 is produced by normal T cells upon anti-CD3 stimulation in humans. Mouse IL-22 expression is also induced in various organs upon lipopolysaccharide injection, suggesting that IL-22 may be involved in inflammatory responses. The functional IL-22 receptor complex consists of two receptor subunits, IL-22R (CRF29) and IL-10Rbeta (CRF24), belonging to the class II cytokine receptor family.
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Specifications
- Conjugation:Unconjugated
- Protein Function:Interleukins
- Protein/peptide type:Recombinant
- Source:CHO cells
- Species:Mouse
- Storage conditions:–20 °C
- Endotoxin content:<0.1EU/µg
- Biological activity:Measured using CTLL-s indicator cells. Specific Activity: 1-1.5 x106 Units/mg.
- Gene ID:NP_058667.1
- Protein synonyms:IL-10-related T Cell-derived-inducible Factor|Interleukin-22
- Protein/peptide name:IL-22
- Purity:98%
- Endotoxin level:Low
- Formulation:Lyophilized from 0.2µm-filtered solution in PBS.
- Shipping temperature:-20 °C, Blue Ice