Human Recombinant PLGF (from Insect Cells (Sf9))

Supplier: Adipogen

Supplier: Adipogen

About this item

Human placenta growth factor-1 (PLGF-1; PLGF) binds to the receptor FLT1/VEGFR-1. It acts as a potent chemoattractant for monocytes and only as a very weak mitogen for some endothelial cell types. The physiological function in vivo is still controversial. In several reports it was shown not to be a potent mitogen for endothelial cells and not angiogenic in vivo by using different assays. It was shown that PLGF from cell culture supernatants was angiogenic in the CAM assay and in the rabbit cornea assay.

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Specifications

Conjugation:
Unconjugated
Protein/peptide type:
Recombinant
Source:
Insect cells (Sf9)
Species:
Human
Storage conditions:
–20 °C
Biological activity:
Measured by its ability to bind to immobilized rhsFlt-1 in a functional ELISA. Recombinant human PLGF can bind to immobilized rhsFlt-1 (100ng/well) with a linear range at 0.5-10ng/ml.
Gene ID:
P49763
Protein synonyms:
PLGF-1|Placenta Growth Factor|PLGF-131
Protein/peptide name:
PLGF
Purity:
95%
Molecular weight:
~34kDa (dimer)
Formulation:
Lyophilized
Shipping temperature:
-20 °C, Blue Ice