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- Conjugation:Unconjugated
- Protein/peptide type:Recombinant
- Source:HEK293 cells
- Species:Mouse
- Size:50 µg
- Storage conditions:–20 °C
- Endotoxin content:<0.01EU/µg
- Gene ID:Q9JKF4
- Protein synonyms:Dendritic Cell-associated C-type Lectin 2|DC-associated C-type Lectin 2|C-type Lectin Superfamily Member 10
- Protein/peptide name:Dectin-2
- Purity:95%
- Molecular weight:~58kDa (SDS-PAGE)
- Endotoxin level:Low
- Concentration:1mg/ml after reconstitution.
- Formulation:Lyophilized. Contains PBS.
- Shipping temperature:-20 °C, Blue Ice
- Cat. no.:102980-270
- Supplier No.:AG40B0139C050
Dectin-1 and dectin-2 are type II transmembrane proteins of the C-type lectin family. They contain single carbohydrate recognition domains (CRDs) in their extracellular region. Dectin-1 and dectin-2 are expressed in macrophages and dendritic cells. Dectin-1 recognizes beta-glucans with its CRD and signals through its immunoreceptor tyrosine-based activation motif (ITAM)-like motif in the cytoplasmic domain, whereas dectin-2 recognizes alpha-mannans and transduces its signal through association with the ITAM-containing Fc receptor gamma-chain.