Recombinant Irisin (from CHO cells)

Supplier: Adipogen

Supplier: Adipogen

About this item

Irisin is a recently described exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin activates beige fat cells (beige cells have a gene expression pattern distinct from either white or brown fat and are preferentially sensitive to the polypeptide hormone Irisin). Irisin is cleaved from the type I membrane protein FNDC5 and improves systemic metabolism by increasing energy expenditure.

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Specifications

Conjugation:
Unconjugated
Protein/peptide type:
Recombinant
Source:
CHO cells
Storage conditions:
–20 °C
Endotoxin content:
<0.01EU/µg
Biological activity:
Activates brown adipocyte markers Ucp1 and Cidec in murine subcutaneous adipocytes at 10ng/ml [Lit. 1].
Gene ID:
Q8NAU1
Protein synonyms:
FNDC5 (cleaved)|Fibronectin Type III Domain-containing Protein 5 (cleaved)|Fibronectin Type III Repeat-containing Protein 2 (cleaved)
Protein/peptide name:
Irisin
Purity:
95%
Molecular weight:
~26kDa
Endotoxin level:
Low
Concentration:
0.1mg/ml after reconstitution.
Formulation:
Lyophilized. Contains PBS.
Shipping temperature:
-20 °C, Blue Ice