Human Recombinant FasL (soluble) (from HEK293 cells)

Supplier: Adipogen

Supplier: Adipogen

About this item

Fc (human):FasL, Soluble (human) is a high activity construct in which two trimeric FasL are artificially linked via the Fc binding domain of human IgG1. This construct very effectively simulates the natural membrane-assisted aggregation of FasL in vivo. FasL is a cytokine that binds to TNFRSF6/Fas, a receptor that transduces the apoptotic signal into cells. It is involved in cytotoxic T cell mediated apoptosis and in T cell development.

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Specifications

Conjugation:
Unconjugated
Protein/peptide type:
Recombinant
Source:
HEK293 cells
Species:
Human
Storage conditions:
–20 °C
Endotoxin content:
<0.01EU/µg
Biological activity:
Induces apoptosis of human Jurkat T cells at a concentration of <0.2ng/ml.
Gene ID:
P48023
Protein synonyms:
TNFSF6|CD178|APO-1L|CD95L|Fas Ligand
Protein/peptide name:
FasL (soluble)
Purity:
95%
Molecular weight:
~50kDa (SDS-PAGE)
Endotoxin level:
Low
Concentration:
0.1mg/ml after reconstitution.
Formulation:
Lyophilized. Contains PBS.
Shipping temperature:
-20 °C, Blue Ice