Human Beta-Amyloid (1-42)

Beta-Amyloid (1-42) peptide, a major component of amyloid plaques, accumulates in neurons of Alzheimer’s disease brains. Biochemical analysis of the amyloid peptides isolated from Alzheimer’s disease brain indicates that Beta-Amyloid (1-42) is the principal species associated with senile plaque amyloids, while Beta-Amyloid (1-40) is more abundant in cerebrovascular amyloid deposit.
Sequence: DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
Molecular Weight: 4514.1 Da
% Peak Area by HPLC: ≥95
Peptide Content: ≥ 60%
Storage condition: -20°C

Lee, HJ., et al. (2016). Effects of hydroxyl group variations on a flavonoid backbone toward modulation of metal-free and metal-induced amyloid-β aggregation Inorg. Chem. Front.,3 381

Citations:
Derrick, J., et al. (2016). Importance of the dimethylamino functionality on a multifunctional framework for regulating metals, Amyloid-β, and oxidative stress in Alzheimer’s Disease Inorg. Chem. doi: 10.1021/acs.inorgchem.6b00525

Lee, HJ., et al. (2016). Effects of hydroxyl group variations on a flavonoid backbone toward modulation of metal-free and metal-induced amyloid-β aggregation Inorg. Chem. Front.,3 381

Mandler, M. et al. (2015). Tailoring the antibody response to aggregated Aß using novel Alzheimer-Vaccines PLoS One doi:10.1371/journal.pone.0115237.

Mandler, M. et al. (2015). Tailoring the antibody response to aggregated Aß using novel Alzheimer-Vaccines PLoS One doi:10.1371/journal.pone.0115237.

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Conjugation:
Unconjugated
Species:
Human
Protein synonyms:
beta amyloid 1-42|abeta (1-42)|amyloid 1-42|amyloid beta (1-42)
Protein/peptide name:
beta-Amyloid (1-42)
Storage conditions:
–20 °C
Purity:
95%
Molecular weight:
4514.1 Da
Sequence:
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
Shipping temperature:
ambient