Human Recombinant NAPRTase (from E. coli)

Catalog # 75794-320

Supplier: Prosci

CAS Number:

Catalog # 75794-320

Supplier: Prosci

Supplier Number: 90-363

CAS Number:

Specifications

Enzyme type:
Recombinant
Source:
E. coli
Species:
Human
Size:
50 μg
Tag sequence:
His Tag
Storage conditions:
Stable for at least 6 months after receipt when stored at –80 °C.
Enzyme name:
NAPRTase
Enzyme activity:
~0.27 U/mg protein. One unit is defined as the amount of enzyme that synthesizes 1umol nicotinic acid mononucleotide (NaMN) per min.
Enzyme synonyms:
Nicotinate Phosphoribosyltransferase, FHA-HIT-interacting Protein, FHIP, EC 2.4.2.11
Purity:
>98% (SDS-PAGE)
Formulation:
Liquid, In 50 mM HEPES/KOH pH 7.5 containing 300 mM potassium chloride and 10 mM DTT.
Cat. no.:
75794-320
Supplier No.:
90-363

Specifications

About this item

Human nicotinate phosphoribosyltransferase (NAPRTase) is localized in the cytoplasm and is involved in biological processes such as NAD biosynthetic and metabolic processes, nicotinamide metabolic process, nicotinate nucleotide salvage, response to oxidative stress and water-soluble vitamin metabolic process

This recombinant proteins is for research use only.

Fusion-Tag: His Tag

It functions by catalyzing the conversion of nicotinic acid (NA) to NA mononucleotide (NaMN) and is essential for NA to increase cellular NAD levels and prevent oxidative stress of the cells. It is a crucial factor in the NAD+ biosynthesis pathway. Catalytic activity: Beta-nicotinate D-ribonucleotide + diphosphate = nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate.