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Human Recombinant ST6GAL1 (from Cells)
Human Recombinant ST6GAL1 (from Cells)
Catalog # 75789-580
Supplier:  Prosci
CAS Number:  
Human Recombinant ST6GAL1 (from Cells)
Catalog # 75789-580
Supplier:  Prosci
Supplier Number:  91-452
CAS Number:  

Specifications

  • Protein/peptide type:
    Recombinant
  • Source:
    Cells
  • Species:
    Human
  • Size:
    0.05 mg
  • Tag sequence:
    C-6 His tag
  • Storage conditions:
    Store at −20 °C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
  • Endotoxin content:
    <0.1 ng/ug (1 IEU/ug) as determined by LAL test.
  • Protein synonyms:
    ST6GAL1|6-Sialyltransferase 1|CMP-N-Acetylneuraminate-Beta-Galactosamide-Alpha-2|Beta-Galactoside Alpha-2|ST6GalI|Alpha 2|ST6Gal I|B-Cell Antigen CD75|6-ST 1|Sialyltransferase 1|SIAT1
  • Protein/peptide name:
    ST6GAL1
  • Purity:
    > 95% as determined by reducing SDS-PAGE
  • Molecular weight:
    44.6 kD
  • Sequence:
    Lys27-Cys406
  • Formulation:
    Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 150mM NaCl, pH 8.0. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
  • Tested applications:
    Bioassay
  • Cat. no.:
    75789-580
  • Supplier No.:
    91-452

Specifications

About this item

The ST6GAL1 gene encodes beta -Galactosamide alpha-2,6-Sialyltransferase 1. It is a type II membrane protein and is localized to the trans-Golgi network. It catalyzes 2,6-sialylation of Gal beta 1,4-GlcNAc structures on N-glycans. ST6GAL1 is highly expressed in the liver and other tissues. ST6GAL1 deficiency causes abnormalities in B-cell immunoreactivity. The expression and activity of ST6GAL1 are associated with tumor metastasis in breast and colon cancers. The majority of ST6GAL1 in the liver is cleaved and secreted into the serum and may be used as a biomarker for hepatitis diseases.

  • Fusion-Tag: C-6 His tag

This recombinant protein can be used for biological assays. For research use only.