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Human Recombinant SLAM (from Cells)
Human Recombinant SLAM (from Cells)
  75789-254
 :  Prosci
 :  
Human Recombinant SLAM (from Cells)
  75789-254
 :  Prosci
 :  91-289
 :  
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To order chemicals, medical devices, or other restricted products, please provide identification that includes your business name and shipping address via email [email protected] or fax 484.881.5997 referencing your VWR account number. Acceptable forms of identification are:

  • • Issued document with your organization's Federal Tax ID Number
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  • • Any other Government ID that includes the business name and address

Avantor will not lift restrictions for residential shipping addresses.

 

  • Protein/peptide type:
    Recombinant
  • Source:
    Cells
  • Species:
    Human
  • Size:
    0.05 mg
  • Tag sequence:
    C-6 His tag
  • Storage conditions:
    Lyophilized protein should be stored at −20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at −20 °C for 3 months.
  • Endotoxin content:
    <0.1 ng/ug (1 IEU/ug) as determined by LAL test.
  • Protein synonyms:
    CD150|CDw150|IPO-3|Signaling Lymphocytic Activation Molecule|SLAMF1|SLAM
  • Protein/peptide name:
    Slam
  • Purity:
    > 95% as determined by reducing SDS-PAGE
  • Molecular weight:
    25.33 kD
  • Sequence:
    Ala21-Pro237
  • Formulation:
    Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
  • Tested applications:
    For Biological Assays
  • Cat. no.:
    75789-254
  • Supplier No.:
    91-289

 

 

SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates.

  • Fusion-Tag: C-6 His tag

This recombinant protein can be used for biological assays. For research use only.