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Human Recombinant Phosphomannomutase 2 (from E. coli)
Human Recombinant Phosphomannomutase 2 (from E. coli)
Catalog # 75789-176
Supplier:  Prosci
CAS Number:  
Human Recombinant Phosphomannomutase 2 (from E. coli)
Catalog # 75789-176
Supplier:  Prosci
Supplier Number:  91-230
CAS Number:  

Specifications

  • Enzyme type:
    Recombinant
  • Source:
    E. coli
  • Species:
    Human
  • Size:
    0.05 mg
  • Tag sequence:
    C-6 His tag
  • Storage conditions:
    Store at −20 °C, stable for 6 months after receipt. Please minimize freeze−thaw cycles.
  • Endotoxin content:
    <0.1 ng/ug (1 IEU/ug) as determined by LAL test.
  • Enzyme name:
    Phosphomannomutase 2
  • Enzyme synonyms:
    Phosphomannomutase 2, PMM 2, PMM2
  • Purity:
    >95% as determined by reducing SDS-PAGE
  • Molecular weight:
    29.1 kD
  • Sequence:
    Met1-Ser246
  • Formulation:
    Supplied as a 0.2 µm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
  • Tested applications:
    Bioassay
  • Cat. no.:
    75789-176
  • Supplier No.:
    91-230

Specifications

About this item

Phosphomannomutase 2 (PMM2) is an enzyme that is a member of the highly variable methyltransferase superfamily

This recombinant protein can be used for biological assays. For research use only.

Fusion-Tag: C-6 His tag

PMM2 is a cytoplasmic protein and catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate.In addition, PMM2 involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose that required for a number of critical mannosyl transfer reactions. Defects in PMM2 can results in congenital disorder of glycosylation type 1A (CDG1A). Congenital disorders of glycosylation are metabolic deficiencies in glycoprotein biosynthesis that usually cause severe mental and psychomotor retardation.