NT-3 is a neurotrophic factor structurally related to β-NGF, BDNF, and NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. NT-3 is expressed by neurons of the central nervous systems, and can signal through the trk receptors. NT-3 promotes the growth and survival of nerve and glial cells. The amino acid sequences of human, murine and rat NT-3 are identical. Recombinant Human NT-3 is a noncovalently linked homodimer of two 13.6 kDa polypeptide monomers (240 total amino acid residues).
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- Conjugation:Unconjugated
- Protein Function:Cytokines and Growth Factors
- Protein/peptide type:Recombinant
- Source:E. coli
- Species:Human
- Storage conditions:Store at –20 °C prior to reconstitution.
- Endotoxin content:>0.1 ng/μg
- Biological activity:Biological Activity tests can vary. Please refer to the Product CoA for information.
- Form:Lyophilized
- Gene ID:4908 P20783
- Reconstitution instructions:Reconstitution instructions can vary. Please refer to the product CoA for info.
- Protease-free:Y
- Protein synonyms:Nerve Growth Factor-2 (NGF-2)|Neurotrophin-3|HGNF|Neurotrophic factor
- Protein/peptide name:NT-3
- Purity:0.98
- Molecular weight:27.2 kDa
- Sequence:MYAEHKSHRG EYSVCDSESL WVTDKSSAID IRGHQVTVLG EIKTGNSPVK QYFYETRCKE ARPVKNGCRG IDDKHWNSQC KTSQTYVRAL TSENNKLVGW RWIRIDTSCV CALSRKIGRT
- Endotoxin level:Low
- Formulation:Formulation can vary. Please refer to product CoA for information.
- Shipping temperature:Ambient