Human Recombinant CTGF (from E. coli)
About this item
CTGF is a member of the CCN family of secreted cysteine-rich regulatory proteins, and is the major mitogenic and chemoattractant protein produced by umbilical vein and vascular endothelial cells. CTGF stimulates the proliferation and differentiation of chondrocytes, induces angiogenesis, promotes cell adhesion of fibroblasts, endothelial and epithelial cells, and binds to IGF, TGF β1 and BMP-4. Cell migration and adhesion are signaled through binding to specific cell surface integrins and to heparin sulfate proteoglycans CTGF (98 a.a.), a lower molecular weight isoform containing the C-terminal portion of the full length CTGF protein, exerts full heparin binding, cell adhesion, and mitogenic CTGF activity. Mature Human CTGF is a 38.0 kDa secreted protein containing 323 amino acid residues. CTGF is comprised of four distinct structural domains (modules), which are identified as IGF binding protein (IGFBP), von Willebrand Factor C (VWFC), thrombospondin type-I (TSP type-I), and C-terminal cysteine knot-like (CTCK) domains. Full length CTGF can be proteolytically cleaved in certain tissues to yield N-terminal truncated isoforms, which, depending on the isoform, contain only the TSP type-I and CTCK domains or contain only the CTCK domain. Recombinant Human CTGF is an 11.0 kDa protein consisting of 97 amino acid residues.
Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.
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- Item requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.
- Return Policy
Product Details & Documents
CTGF is a member of the CCN family of secreted cysteine-rich regulatory proteins, and is the major mitogenic and chemoattractant protein produced by umbilical vein and vascular endothelial cells. CTGF stimulates the proliferation and differentiation of chondrocytes, induces angiogenesis, promotes cell adhesion of fibroblasts, endothelial and epithelial cells, and binds to IGF, TGF β1 and BMP-4. Cell migration and adhesion are signaled through binding to specific cell surface integrins and to heparin sulfate proteoglycans CTGF (98 a.a.), a lower molecular weight isoform containing the C-terminal portion of the full length CTGF protein, exerts full heparin binding, cell adhesion, and mitogenic CTGF activity. Mature Human CTGF is a 38.0 kDa secreted protein containing 323 amino acid residues. CTGF is comprised of four distinct structural domains (modules), which are identified as IGF binding protein (IGFBP), von Willebrand Factor C (VWFC), thrombospondin type-I (TSP type-I), and C-terminal cysteine knot-like (CTCK) domains. Full length CTGF can be proteolytically cleaved in certain tissues to yield N-terminal truncated isoforms, which, depending on the isoform, contain only the TSP type-I and CTCK domains or contain only the CTCK domain. Recombinant Human CTGF is an 11.0 kDa protein consisting of 97 amino acid residues.
Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.
Specifications for Product Family
Specifications
Specifications
- Catalog No:
- 10779-174
- 10779-176
- 10779-178
- 10779-180
- 10779-182
- Protein/peptide name:
- CTGF
- CTGF
- CTGF
- CTGF
- CTGF
- Protein synonyms:
- Hypertrophic chondrocyte-specific protein 24 (HCS24)|CCN2|Connective Tissue Growth Factor
- Hypertrophic chondrocyte-specific protein 24 (HCS24)|CCN2|Connective Tissue Growth Factor
- Hypertrophic chondrocyte-specific protein 24 (HCS24)|CCN2|Connective Tissue Growth Factor
- Hypertrophic chondrocyte-specific protein 24 (HCS24)|CCN2|Connective Tissue Growth Factor
- Hypertrophic chondrocyte-specific protein 24 (HCS24)|CCN2|Connective Tissue Growth Factor
- Protein/peptide type:
- Recombinant
- Recombinant
- Recombinant
- Recombinant
- Recombinant
- Protein Function:
- Cytokines and Growth Factors
- Cytokines and Growth Factors
- Cytokines and Growth Factors
- Cytokines and Growth Factors
- Cytokines and Growth Factors
- Species:
- Human
- Human
- Human
- Human
- Human
- Source:
- E. coli
- E. coli
- E. coli
- E. coli
- E. coli
- Conjugation:
- Unconjugated
- Unconjugated
- Unconjugated
- Unconjugated
- Unconjugated
- Gene ID:
- 1490 P29279
- 1490 P29279
- 1490 P29279
- 1490 P29279
- 1490 P29279
- Sequence:
- GKKCIRTPKI SKPIKFELSG CTSMKTYRAK FCGVCTDGRC CTPHRTTTLP VEFKCPDGEV MKKNMMFIKT CACHYNCPGD NDIFESLYYR KMYGDMA
- GKKCIRTPKI SKPIKFELSG CTSMKTYRAK FCGVCTDGRC CTPHRTTTLP VEFKCPDGEV MKKNMMFIKT CACHYNCPGD NDIFESLYYR KMYGDMA
- GKKCIRTPKI SKPIKFELSG CTSMKTYRAK FCGVCTDGRC CTPHRTTTLP VEFKCPDGEV MKKNMMFIKT CACHYNCPGD NDIFESLYYR KMYGDMA
- GKKCIRTPKI SKPIKFELSG CTSMKTYRAK FCGVCTDGRC CTPHRTTTLP VEFKCPDGEV MKKNMMFIKT CACHYNCPGD NDIFESLYYR KMYGDMA
- GKKCIRTPKI SKPIKFELSG CTSMKTYRAK FCGVCTDGRC CTPHRTTTLP VEFKCPDGEV MKKNMMFIKT CACHYNCPGD NDIFESLYYR KMYGDMA
- Protease-free:
- Y
- Y
- Y
- Y
- Y
- Endotoxin level:
- Low
- Low
- Low
- Low
- Low
- Endotoxin content:
- >0.1 ng/μg
- >0.1 ng/μg
- >0.1 ng/μg
- >0.1 ng/μg
- >0.1 ng/μg
- Biological activity:
- Biological Activity tests can vary. Please refer to the Product CoA for information.
- Biological Activity tests can vary. Please refer to the Product CoA for information.
- Biological Activity tests can vary. Please refer to the Product CoA for information.
- Biological Activity tests can vary. Please refer to the Product CoA for information.
- Biological Activity tests can vary. Please refer to the Product CoA for information.
- Purity:
- 0.95
- 0.95
- 0.95
- 0.95
- 0.95
- Form:
- Lyophilized
- Lyophilized
- Lyophilized
- Lyophilized
- Lyophilized
- Formulation:
- Formulation can vary. Please refer to product CoA for information.
- Formulation can vary. Please refer to product CoA for information.
- Formulation can vary. Please refer to product CoA for information.
- Formulation can vary. Please refer to product CoA for information.
- Formulation can vary. Please refer to product CoA for information.
- Molecular weight:
- 11 kDa
- 11 kDa
- 11 kDa
- 11 kDa
- 11 kDa
- Reconstitution instructions:
- Reconstitution instructions can vary. Please refer to the product CoA for info.
- Reconstitution instructions can vary. Please refer to the product CoA for info.
- Reconstitution instructions can vary. Please refer to the product CoA for info.
- Reconstitution instructions can vary. Please refer to the product CoA for info.
- Reconstitution instructions can vary. Please refer to the product CoA for info.
- Storage conditions:
- Store at –20 °C prior to reconstitution.
- Store at –20 °C prior to reconstitution.
- Store at –20 °C prior to reconstitution.
- Store at –20 °C prior to reconstitution.
- Store at –20 °C prior to reconstitution.
- Shipping temperature:
- Ambient
- Ambient
- Ambient
- Ambient
- Ambient
Specifications
Product Family Options
Product Information
- SizeOriginAvailabilityPrice
- Supplier Number: 120-19-5UGItem requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.Specifications:
More
Specifications
Cat. No.10779-174Protein/peptide nameCTGFProtein synonymsHypertrophic chondrocyte-specific protein 24 (HCS24)|CCN2|Connective Tissue Growth FactorProtein/peptide typeRecombinantProtein FunctionCytokines and Growth FactorsSpeciesHumanSourceE. coliConjugationUnconjugatedGene ID1490 P29279SequenceGKKCIRTPKI SKPIKFELSG CTSMKTYRAK FCGVCTDGRC CTPHRTTTLP VEFKCPDGEV MKKNMMFIKT CACHYNCPGD NDIFESLYYR KMYGDMAProtease-freeYEndotoxin levelLowEndotoxin content>0.1 ng/μgBiological activityBiological Activity tests can vary. Please refer to the Product CoA for information.Purity0.95FormLyophilizedFormulationFormulation can vary. Please refer to product CoA for information.Molecular weight11 kDaReconstitution instructionsReconstitution instructions can vary. Please refer to the product CoA for info.Storage conditionsStore at –20 °C prior to reconstitution.Shipping temperatureAmbient - Supplier Number: 120-19-20UGItem requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.Specifications:
More
Specifications
Cat. No.10779-176Protein/peptide nameCTGFProtein synonymsHypertrophic chondrocyte-specific protein 24 (HCS24)|CCN2|Connective Tissue Growth FactorProtein/peptide typeRecombinantProtein FunctionCytokines and Growth FactorsSpeciesHumanSourceE. coliConjugationUnconjugatedGene ID1490 P29279SequenceGKKCIRTPKI SKPIKFELSG CTSMKTYRAK FCGVCTDGRC CTPHRTTTLP VEFKCPDGEV MKKNMMFIKT CACHYNCPGD NDIFESLYYR KMYGDMAProtease-freeYEndotoxin levelLowEndotoxin content>0.1 ng/μgBiological activityBiological Activity tests can vary. Please refer to the Product CoA for information.Purity0.95FormLyophilizedFormulationFormulation can vary. Please refer to product CoA for information.Molecular weight11 kDaReconstitution instructionsReconstitution instructions can vary. Please refer to the product CoA for info.Storage conditionsStore at –20 °C prior to reconstitution.Shipping temperatureAmbient - Supplier Number: 120-19-100UGItem requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.Specifications:
More
Specifications
Cat. No.10779-178Protein/peptide nameCTGFProtein synonymsHypertrophic chondrocyte-specific protein 24 (HCS24)|CCN2|Connective Tissue Growth FactorProtein/peptide typeRecombinantProtein FunctionCytokines and Growth FactorsSpeciesHumanSourceE. coliConjugationUnconjugatedGene ID1490 P29279SequenceGKKCIRTPKI SKPIKFELSG CTSMKTYRAK FCGVCTDGRC CTPHRTTTLP VEFKCPDGEV MKKNMMFIKT CACHYNCPGD NDIFESLYYR KMYGDMAProtease-freeYEndotoxin levelLowEndotoxin content>0.1 ng/μgBiological activityBiological Activity tests can vary. Please refer to the Product CoA for information.Purity0.95FormLyophilizedFormulationFormulation can vary. Please refer to product CoA for information.Molecular weight11 kDaReconstitution instructionsReconstitution instructions can vary. Please refer to the product CoA for info.Storage conditionsStore at –20 °C prior to reconstitution.Shipping temperatureAmbient - Supplier Number: 120-19-250UGItem requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.Specifications:
More
Specifications
Cat. No.10779-180Protein/peptide nameCTGFProtein synonymsHypertrophic chondrocyte-specific protein 24 (HCS24)|CCN2|Connective Tissue Growth FactorProtein/peptide typeRecombinantProtein FunctionCytokines and Growth FactorsSpeciesHumanSourceE. coliConjugationUnconjugatedGene ID1490 P29279SequenceGKKCIRTPKI SKPIKFELSG CTSMKTYRAK FCGVCTDGRC CTPHRTTTLP VEFKCPDGEV MKKNMMFIKT CACHYNCPGD NDIFESLYYR KMYGDMAProtease-freeYEndotoxin levelLowEndotoxin content>0.1 ng/μgBiological activityBiological Activity tests can vary. Please refer to the Product CoA for information.Purity0.95FormLyophilizedFormulationFormulation can vary. Please refer to product CoA for information.Molecular weight11 kDaReconstitution instructionsReconstitution instructions can vary. Please refer to the product CoA for info.Storage conditionsStore at –20 °C prior to reconstitution.Shipping temperatureAmbient - Supplier Number: 120-19-500UGItem requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.Specifications:
More
Specifications
Cat. No.10779-182Protein/peptide nameCTGFProtein synonymsHypertrophic chondrocyte-specific protein 24 (HCS24)|CCN2|Connective Tissue Growth FactorProtein/peptide typeRecombinantProtein FunctionCytokines and Growth FactorsSpeciesHumanSourceE. coliConjugationUnconjugatedGene ID1490 P29279SequenceGKKCIRTPKI SKPIKFELSG CTSMKTYRAK FCGVCTDGRC CTPHRTTTLP VEFKCPDGEV MKKNMMFIKT CACHYNCPGD NDIFESLYYR KMYGDMAProtease-freeYEndotoxin levelLowEndotoxin content>0.1 ng/μgBiological activityBiological Activity tests can vary. Please refer to the Product CoA for information.Purity0.95FormLyophilizedFormulationFormulation can vary. Please refer to product CoA for information.Molecular weight11 kDaReconstitution instructionsReconstitution instructions can vary. Please refer to the product CoA for info.Storage conditionsStore at –20 °C prior to reconstitution.Shipping temperatureAmbient
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