Human Recombinant BMP-13/CDMP-2 (from E. coli)

About this item

BMP-13 is expressed in hypertrophic chondrocytes during embryonic development of long bones. Continued postnatal expression of BMP-13 in articular cartilage suggests that it plays a regulatory role in the growth and maintenance of articular cartilage. Adenovirus-mediated BMP-13 gene transfer to rabbit bone marrow stem cells have been reported to augment periosteal repair of osteochondral defects. The functional form of BMP-13/CDMP-2 is a disulfide-linked homodimer of two 120 amino-acid polypeptide chains. This 27.5 kDa protein is obtained by proteolytic processing of a biologically inactive precursor protein of 97.7 kDa. Recombinant Human BMP-13/CDMP-2 is a 27.0 kDa homodimeric disulfide-linked protein consisting of two 120 amino acid polypeptide chains.

Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.

Restricted Products: To process your orders without delay, please provide the required business documentation to purchase this product.

To order chemicals, medical devices, or other restricted products, please provide identification that includes your business name and shipping address via email [email protected] or fax 484.881.5997 referencing your VWR account number. Acceptable forms of identification are:

• Issued document with your organization's Federal Tax ID Number
• Government issued document with your organization's Resale Tax ID Number
• Any other Government ID that includes the business name and address

Avantor will not lift restrictions for residential shipping addresses.

Specifications

Conjugation:
Unconjugated
Protein Function:
Cytokines and Growth Factors
Protein/peptide type:
Recombinant
Source:
E. coli
Species:
Human
Storage conditions:
Store at –20 °C prior to reconstitution.
Endotoxin content:
>0.1 ng/μg
Biological activity:
Biological Activity tests can vary. Please refer to the Product CoA for information.
Form:
Lyophilized
Gene ID:
392255 Q6KF10
Reconstitution instructions:
Reconstitution instructions can vary. Please refer to the product CoA for info.
Protease-free:
Y
Protein synonyms:
Bone Morphogenetic Protein-13|Cartilage-Derived Morphogenetic Protein-2 (CDMP-2)|GDF-6
Protein/peptide name:
BMP-13/CDMP-2
Purity:
0.95
Molecular weight:
27 kDa
Sequence:
TAFASRHGKR HGKKSRLRCS KKPLHVNFKE LGWDDWIIAP LEYEAYHCEG VCDFPLRSHL EPTNHAIIQT LMNSMDPGST PPSCCVPTKL TPISILYIDA GNNVVYKQYE DMVVESCGCR
Endotoxin level:
Low
Formulation:
Formulation can vary. Please refer to product CoA for information.
Shipping temperature:
Ambient