RELMβ (Resistin-like molecule β/FIZZ2) is a disulfide-linked, homodimeric protein expressed in the epithelium of the colon and small bowel. The biological functions of RELMβ, and its molecular targets, are not fully known, but it has been suggested that it plays a regulatory role during inflammation, and may also act to establish links among adipose tissue, the intestine and the liver. Interestingly, the molecular structure of RELMβ is highly homologous to that of the adipose-derived cytokines, resistin and RELMα. These proteins share a highly conserved C-terminal domain, characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. Recombinant Murine RELMβ is an 18.0 kDa protein, consisting of two identical 83 amino acid polypeptide chains linked by a single disulfide bond.
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- Conjugation:Unconjugated
- Protein Function:Cytokines and Growth Factors
- Protein/peptide type:Recombinant
- Source:E. coli
- Species:Mouse
- Storage conditions:Store at –20 °C prior to reconstitution.
- Endotoxin content:>0.1 ng/μg
- Biological activity:Biological Activity tests can vary. Please refer to the Product CoA for information.
- Form:Lyophilized
- Gene ID:57263 Q99P86
- Reconstitution instructions:Reconstitution instructions can vary. Please refer to the product CoA for info.
- Protease-free:Y
- Protein synonyms:Resistin-like β|Cysteine-rich secreted protein FIZZ2
- Protein/peptide name:RELMbeta
- Purity:0.98
- Molecular weight:18 kDa
- Sequence:MQCSFESLVD QRIKEALSRQ EPKTISCTSV TSSGRLASCP AGMVVTGCAC GYGCGSWDIR NGNTCHCQCS VMDWASARCC RMA
- Endotoxin level:Low
- Formulation:Formulation can vary. Please refer to product CoA for information.
- Shipping temperature:Ambient