Human Recombinant IGF-BP6 (from (BTI-Tn-5B1-4) Hi-5 Insect cells)

About this item

IGF-BPs control the distribution, function and activity of IGFs in various cell tissues and body fluids. IGF-BP6, which specifically inhibits IGF-II actions, is produced by bone cells and is the major IGF-BP present in cerebrospinal fluid. IGF-BP6 has been shown to inhibit IGF-II-dependent cancers such as neuroblastoma, colon cancer and rhabdomyosarcoma. Recombinant Human IGF-BP6 has a calculated mass of 22.3 kDa and consists of 213 amino acid residues, including the IGF-BP domain and thyroglobulin type-I domain. Recombinant Human IGF-BP6 migrates at an apparent molecular weight of approximately 23.0-30.0 kDa by SDS-PAGE analysis under non-reducing conditions.

Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.

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Specifications

Conjugation:
Unconjugated
Protein Function:
Cytokines and Growth Factors
Protein/peptide type:
Recombinant
Source:
(BTI-Tn-5B1-4) Hi-5 Insect cells
Species:
Human
Storage conditions:
Store at –20 °C prior to reconstitution.
Endotoxin content:
>0.1 ng/μg
Biological activity:
Biological Activity tests can vary. Please refer to the Product CoA for information.
Form:
Lyophilized
Gene ID:
3489 P24592
Reconstitution instructions:
Reconstitution instructions can vary. Please refer to the product CoA for info.
Protease-free:
Y
Protein synonyms:
Insulin-like Growth Factor-Binding Protein 6|IBP-6
Protein/peptide name:
IGF-BP6
Purity:
0.95
Molecular weight:
22.3 kDa
Sequence:
RCPGCGQGVQ AGCPGGCVEE EDGGSPAEGC AEAEGCLRRE GQECGVYTPN CAPGLQCHPP KDDEAPLRAL LLGRGRCLPA RAPAVAEENP KESKPQAGTA RPQDVNRRDQ QRNPGTSTTP SQPNSAGVQD TEMGPCRRHL DSVLQQLQTE VYRGAQTLYV PNCDHRGFYR KRQCRSSQGQ RRGPCWCVDR MGKSLPGSPD GNGSSSCPTG SSG
Endotoxin level:
Low
Formulation:
Formulation can vary. Please refer to product CoA for information.
Shipping temperature:
Ambient