Human Recombinant sCD23 (from E. coli)

CD23, the low affinity receptor for IgE, belongs to the C-type lectin structural family and plays a role in the regulation of IgE synthesis and IgE mediated activities. It is found both as a transmembrane receptor protein and in a soluble form, which is generated by proteolytic cleavage of membrane-bound CD23. The predominant soluble form of CD23 (sCD23) consists of 172 amino acids corresponding to the extracellular domain of the full length precursor. sCD23, in addition to binding IgE, also exerts a number of IgE-independent activities, such as promoting the activation and differentiation of B-cells and stimulating the release of pro-inflammatory cytokines from monocytes. Recombinant Human sCD23 is a 19.2 kDa non-glycosylated protein containing 172 amino-acid residues.

: For research use only. Not for use in diagnostic or therapeutic procedures.

Restricted Products: To process your orders without delay, please provide the required business documentation to purchase this product.

To order chemicals, medical devices, or other restricted products, please provide identification that includes your business name and shipping address via email [email protected] or fax 484.881.5997 referencing your VWR account number. Acceptable forms of identification are:

• Issued document with your organization's Federal Tax ID Number
• Government issued document with your organization's Resale Tax ID Number
• Any other Government ID that includes the business name and address

Avantor will not lift restrictions for residential shipping addresses.

Conjugation:
Unconjugated
Protein Function:
Cytokines and Growth Factors
Protein/peptide type:
Recombinant
Source:
E. coli
Species:
Human
Storage conditions:
Store at –20 °C prior to reconstitution.
Endotoxin content:
>0.1 ng/μg
Biological activity:
Biological Activity tests can vary. Please refer to the Product CoA for information.
Form:
Lyophilized
Gene ID:
2208 P06734
Reconstitution instructions:
Reconstitution instructions can vary. Please refer to the product CoA for info.
Protease-free:
Y
Protein synonyms:
Lymphocyte IgE receptor|BLAST-2|soluble CD23|Fc-epsilon-RII|CD23 antigen
Protein/peptide name:
sCD23
Purity:
0.96
Molecular weight:
19.2 kDa
Sequence:
MELQVSSGFV CNTCPEKWIN FQRKCYYFGK GTKQWVHARY ACDDMEGQLV SIHSPEEQDF LTKHASHTGS WIGLRNLDLK GEFIWVDGSH VDYSNWAPGE PTSRSQGEDC VMMRGSGRWN DAFCDRKLGA WVCDRLATCT PPASEGSAES MGPDSRPDPD GRLPTPSAPL HS
Endotoxin level:
Low
Formulation:
Formulation can vary. Please refer to product CoA for information.
Shipping temperature:
Ambient