Human Recombinant BD1 (from E. coli)
About this item
Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The α-defensins are distinguished from the β-defensins by the pairing of their three disulfide bonds. To date, six human β-defensins have been identified; BD-1, BD-2, BD-3, BD-4, BD-5 and BD-6. β-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they can act as chemoattractants towards immature dendritic cells and memory T cells. The β-defensin proteins are expressed as the C-terminal portion of precursors, and are released by proteolytic cleavage of a signal sequence and, in some cases, a propeptide sequence. β-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. Recombinant Human BD-1 is a 5.0 kDa protein containing 47 amino acid residues.
Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.
6 Options Available Below
- Item requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.
- Return Policy
Product Details & Documents
Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The α-defensins are distinguished from the β-defensins by the pairing of their three disulfide bonds. To date, six human β-defensins have been identified; BD-1, BD-2, BD-3, BD-4, BD-5 and BD-6. β-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they can act as chemoattractants towards immature dendritic cells and memory T cells. The β-defensin proteins are expressed as the C-terminal portion of precursors, and are released by proteolytic cleavage of a signal sequence and, in some cases, a propeptide sequence. β-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. Recombinant Human BD-1 is a 5.0 kDa protein containing 47 amino acid residues.
Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.
Specifications for Product Family
Specifications
Specifications
- Catalog No:
- 10770-762
- 10770-764
- 10770-766
- 10770-768
- 10770-770
- 10770-772
- Protein/peptide name:
- BD1
- BD1
- BD1
- BD1
- BD1
- BD1
- Protein synonyms:
- HBD1|DEFB1|Beta-Defensin 1
- HBD1|DEFB1|Beta-Defensin 1
- HBD1|DEFB1|Beta-Defensin 1
- HBD1|DEFB1|Beta-Defensin 1
- HBD1|DEFB1|Beta-Defensin 1
- HBD1|DEFB1|Beta-Defensin 1
- Protein/peptide type:
- Recombinant
- Recombinant
- Recombinant
- Recombinant
- Recombinant
- Recombinant
- Protein Function:
- Cytokines and Growth Factors
- Cytokines and Growth Factors
- Cytokines and Growth Factors
- Cytokines and Growth Factors
- Cytokines and Growth Factors
- Cytokines and Growth Factors
- Species:
- Human
- Human
- Human
- Human
- Human
- Human
- Source:
- E. coli
- E. coli
- E. coli
- E. coli
- E. coli
- E. coli
- Conjugation:
- Unconjugated
- Unconjugated
- Unconjugated
- Unconjugated
- Unconjugated
- Unconjugated
- Gene ID:
- 1672 P60022
- 1672 P60022
- 1672 P60022
- 1672 P60022
- 1672 P60022
- 1672 P60022
- Sequence:
- GNFLTGLGHR SDHYNCVSSG GQCLYSACPI FTKIQGTCYR GKAKCCK
- GNFLTGLGHR SDHYNCVSSG GQCLYSACPI FTKIQGTCYR GKAKCCK
- GNFLTGLGHR SDHYNCVSSG GQCLYSACPI FTKIQGTCYR GKAKCCK
- GNFLTGLGHR SDHYNCVSSG GQCLYSACPI FTKIQGTCYR GKAKCCK
- GNFLTGLGHR SDHYNCVSSG GQCLYSACPI FTKIQGTCYR GKAKCCK
- GNFLTGLGHR SDHYNCVSSG GQCLYSACPI FTKIQGTCYR GKAKCCK
- Protease-free:
- Y
- Y
- Y
- Y
- Y
- Y
- Endotoxin level:
- Low
- Low
- Low
- Low
- Low
- Low
- Endotoxin content:
- >0.1 ng/μg
- >0.1 ng/μg
- >0.1 ng/μg
- >0.1 ng/μg
- >0.1 ng/μg
- >0.1 ng/μg
- Biological activity:
- Biological Activity tests can vary. Please refer to the Product CoA for information.
- Biological Activity tests can vary. Please refer to the Product CoA for information.
- Biological Activity tests can vary. Please refer to the Product CoA for information.
- Biological Activity tests can vary. Please refer to the Product CoA for information.
- Biological Activity tests can vary. Please refer to the Product CoA for information.
- Biological Activity tests can vary. Please refer to the Product CoA for information.
- Purity:
- 0.98
- 0.98
- 0.98
- 0.98
- 0.98
- 0.98
- Form:
- Lyophilized
- Lyophilized
- Lyophilized
- Lyophilized
- Lyophilized
- Lyophilized
- Formulation:
- Formulation can vary. Please refer to product CoA for information.
- Formulation can vary. Please refer to product CoA for information.
- Formulation can vary. Please refer to product CoA for information.
- Formulation can vary. Please refer to product CoA for information.
- Formulation can vary. Please refer to product CoA for information.
- Formulation can vary. Please refer to product CoA for information.
- Molecular weight:
- 5.0 kDa
- 5.0 kDa
- 5.0 kDa
- 5.0 kDa
- 5.0 kDa
- 5.0 kDa
- Reconstitution instructions:
- Reconstitution instructions can vary. Please refer to the product CoA for info.
- Reconstitution instructions can vary. Please refer to the product CoA for info.
- Reconstitution instructions can vary. Please refer to the product CoA for info.
- Reconstitution instructions can vary. Please refer to the product CoA for info.
- Reconstitution instructions can vary. Please refer to the product CoA for info.
- Reconstitution instructions can vary. Please refer to the product CoA for info.
- Storage conditions:
- Store at –20 °C prior to reconstitution.
- Store at –20 °C prior to reconstitution.
- Store at –20 °C prior to reconstitution.
- Store at –20 °C prior to reconstitution.
- Store at –20 °C prior to reconstitution.
- Store at –20 °C prior to reconstitution.
- Shipping temperature:
- Ambient
- Ambient
- Ambient
- Ambient
- Ambient
- Ambient
Specifications
Product Family Options
Product Information
- SizeOriginAvailabilityPrice
- Supplier Number: 300-51A-5UGItem requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.Specifications:
More
Specifications
Cat. No.10770-762Protein/peptide nameBD1Protein synonymsHBD1|DEFB1|Beta-Defensin 1Protein/peptide typeRecombinantProtein FunctionCytokines and Growth FactorsSpeciesHumanSourceE. coliConjugationUnconjugatedGene ID1672 P60022SequenceGNFLTGLGHR SDHYNCVSSG GQCLYSACPI FTKIQGTCYR GKAKCCKProtease-freeYEndotoxin levelLowEndotoxin content>0.1 ng/μgBiological activityBiological Activity tests can vary. Please refer to the Product CoA for information.Purity0.98FormLyophilizedFormulationFormulation can vary. Please refer to product CoA for information.Molecular weight5.0 kDaReconstitution instructionsReconstitution instructions can vary. Please refer to the product CoA for info.Storage conditionsStore at –20 °C prior to reconstitution.Shipping temperatureAmbient - Supplier Number: 300-51A-20UGItem requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.Specifications:
More
Specifications
Cat. No.10770-764Protein/peptide nameBD1Protein synonymsHBD1|DEFB1|Beta-Defensin 1Protein/peptide typeRecombinantProtein FunctionCytokines and Growth FactorsSpeciesHumanSourceE. coliConjugationUnconjugatedGene ID1672 P60022SequenceGNFLTGLGHR SDHYNCVSSG GQCLYSACPI FTKIQGTCYR GKAKCCKProtease-freeYEndotoxin levelLowEndotoxin content>0.1 ng/μgBiological activityBiological Activity tests can vary. Please refer to the Product CoA for information.Purity0.98FormLyophilizedFormulationFormulation can vary. Please refer to product CoA for information.Molecular weight5.0 kDaReconstitution instructionsReconstitution instructions can vary. Please refer to the product CoA for info.Storage conditionsStore at –20 °C prior to reconstitution.Shipping temperatureAmbient - Supplier Number: 300-51A-100UGItem requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.Specifications:
More
Specifications
Cat. No.10770-766Protein/peptide nameBD1Protein synonymsHBD1|DEFB1|Beta-Defensin 1Protein/peptide typeRecombinantProtein FunctionCytokines and Growth FactorsSpeciesHumanSourceE. coliConjugationUnconjugatedGene ID1672 P60022SequenceGNFLTGLGHR SDHYNCVSSG GQCLYSACPI FTKIQGTCYR GKAKCCKProtease-freeYEndotoxin levelLowEndotoxin content>0.1 ng/μgBiological activityBiological Activity tests can vary. Please refer to the Product CoA for information.Purity0.98FormLyophilizedFormulationFormulation can vary. Please refer to product CoA for information.Molecular weight5.0 kDaReconstitution instructionsReconstitution instructions can vary. Please refer to the product CoA for info.Storage conditionsStore at –20 °C prior to reconstitution.Shipping temperatureAmbient - Supplier Number: 300-51A-250UGItem requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.Specifications:
More
Specifications
Cat. No.10770-768Protein/peptide nameBD1Protein synonymsHBD1|DEFB1|Beta-Defensin 1Protein/peptide typeRecombinantProtein FunctionCytokines and Growth FactorsSpeciesHumanSourceE. coliConjugationUnconjugatedGene ID1672 P60022SequenceGNFLTGLGHR SDHYNCVSSG GQCLYSACPI FTKIQGTCYR GKAKCCKProtease-freeYEndotoxin levelLowEndotoxin content>0.1 ng/μgBiological activityBiological Activity tests can vary. Please refer to the Product CoA for information.Purity0.98FormLyophilizedFormulationFormulation can vary. Please refer to product CoA for information.Molecular weight5.0 kDaReconstitution instructionsReconstitution instructions can vary. Please refer to the product CoA for info.Storage conditionsStore at –20 °C prior to reconstitution.Shipping temperatureAmbient - Supplier Number: 300-51A-500UGItem requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.Specifications:
More
Specifications
Cat. No.10770-770Protein/peptide nameBD1Protein synonymsHBD1|DEFB1|Beta-Defensin 1Protein/peptide typeRecombinantProtein FunctionCytokines and Growth FactorsSpeciesHumanSourceE. coliConjugationUnconjugatedGene ID1672 P60022SequenceGNFLTGLGHR SDHYNCVSSG GQCLYSACPI FTKIQGTCYR GKAKCCKProtease-freeYEndotoxin levelLowEndotoxin content>0.1 ng/μgBiological activityBiological Activity tests can vary. Please refer to the Product CoA for information.Purity0.98FormLyophilizedFormulationFormulation can vary. Please refer to product CoA for information.Molecular weight5.0 kDaReconstitution instructionsReconstitution instructions can vary. Please refer to the product CoA for info.Storage conditionsStore at –20 °C prior to reconstitution.Shipping temperatureAmbient - Supplier Number: 300-51A-1MGItem requires temperature control for storage and delivery with additional fees. It's not eligible for return due to safety and quality concerns. Consider requirements before purchasing.Specifications:
More
Specifications
Cat. No.10770-772Protein/peptide nameBD1Protein synonymsHBD1|DEFB1|Beta-Defensin 1Protein/peptide typeRecombinantProtein FunctionCytokines and Growth FactorsSpeciesHumanSourceE. coliConjugationUnconjugatedGene ID1672 P60022SequenceGNFLTGLGHR SDHYNCVSSG GQCLYSACPI FTKIQGTCYR GKAKCCKProtease-freeYEndotoxin levelLowEndotoxin content>0.1 ng/μgBiological activityBiological Activity tests can vary. Please refer to the Product CoA for information.Purity0.98FormLyophilizedFormulationFormulation can vary. Please refer to product CoA for information.Molecular weight5.0 kDaReconstitution instructionsReconstitution instructions can vary. Please refer to the product CoA for info.Storage conditionsStore at –20 °C prior to reconstitution.Shipping temperatureAmbient
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